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    • Insig-Mediated Regulation of Hepatic Lipid Synthesis 

      Engelking, Luke James (2007-05-22)
      Cholesterol synthesis in mammals is tightly regulated by end-product feedback inhibition. 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) catalyzes a rate determining reaction that is highly regulated by transcriptional ...