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    • Signal Specific Ubiquitination and Degradation of IkBa 

      Hakala, Kevin William (2003-10-08)
      The transcription factor Nuclear Factor kB (NF-kB) is retained in the cytoplasm by the action of its inhibitor IkB. Upon phosphorylation by the IKK complex, IkB is rapidly ubiquitinated and targeted for 26S proteasome ...