Browsing by Author "Jakubowski, Brandon"
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Generation of a Novel D. melanogaster Platform to Elucidate Oncogenic Activity of Common Human p53 Missense Mutants
Jakubowski, Brandon (2014-02-04)The tumor suppressor p53 prevents uncontrolled cell growth by three separate mechanisms: inducing apoptosis, initiating cell-cycle arrest, and activating DNA repair mechanisms in response to cell damage. Due to its central ...