Now showing items 1-3 of 3

    • Activated RhoA Positively Regulates Exchange Activity of PDZ-RhoGEF 

      Medina, Frank J., III 1979- (2012-12-06)
      RhoA plays a key role in regulation of the actin cytoskeleton, cell migration and cell shape. Rho GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This cycle is mediated by guanine nucleotide ...
    • Regulation of Cell Migration by WNK1 

      Estrada, Armando, III 1980- (2012-12-06)
      Cell motility is an immensely complex process that involves reorganization of the cytoskeleton, and consequent membrane deformation, triggered by a variety of motogenic stimuli, including growth and chemotactic factors, ...
    • Regulation of p190RhoGEF by Activated Rho and Rac GTPases: Amplification and Crosstalk 

      Dada, Olugbenga Adesola; 0000-0001-9847-7197 (2017-04-14)
      The Rho family of monomeric GTPases regulates a wide range of cellular processes including cytoskeletal structure, motility, cell division, gene transcription, vesicular transport, and various enzymatic activities. Activation ...