Browsing by Subject "Labor, Obstetric"
Now showing items 1-6 of 6
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Antagonistic Roles of miR-199a-3p/miR-214 and the miR-200 Family in the Regulation of Uterine Contractility During Pregnancy and Labor
(2014-02-03)Progesterone (P4) and estradiol-17β (E2) play critical and opposing roles in regulating myometrial quiescence and contractility during pregnancy and labor (Kamel et al., 2010). While these contrasting hormonal effects are ... -
Calcitriol Treatment Suppresses Contraction-Associated Gene Expression in Pregnant Mice Near Term
(2018-01-23)Preterm birth (PTB) is the leading cause of infant mortality during the first four weeks of life world-wide. This is due, in part, to our incomplete understanding of the mechanisms that mediate uterine quiescence during ... -
The Murine Amniotic Fluid Macrophage: Upregulation of Classical and Alternative Activation Markers Prior to Labor at Term
(2010-11-02)The initiation of labor at term and preterm is associated with an inflammatory response, with increased interleukins in amniotic fluid (AF) and infiltration of the myometrium by neutrophils and macrophages (MΦ). Whereas, ... -
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Post-Transcriptional Regulation by microRNAS in Pregnancy and Parturition
(2012-08-15)Throughout most of pregnancy, uterine quiescence is maintained by increased progesterone receptor (PR) transcriptional activity, while spontaneous labor is initiated/facilitated by a concerted series of biochemical events ... -
The Role of Vitamin D Metabolism in the Timing of Birth
(2018-01-23)Preterm birth (PTB, <37 weeks of gestation) is the leading cause of neonatal mortality and morbidity. Both term and preterm labor are associated with increased levels of proinflammatory cytokines within fetal and maternal ...