Now showing items 1-2 of 2

    • Modulating DNA Damage Responses for Improved Breast Cancer Therapy 

      Ilcheva, Mariya Ilcheva (2015-04-06)
      The main focus of this work is to improve the efficacy of breast cancer therapy, either by utilizing novel agents that induce specific types of DNA damage resulting in metabolic changes, or by modulating factors that are ...
    • Precursor-Directed Identification of Natural Product Scaffolds 

      Brumley, David Anderson; 0000-0001-5083-5717 (2017-04-17)
      The rapid generation of natural product analogs is a fundamental challenge in both the optimization of medicinal potency and exploration of novel biological activity. Previous work with Streptomyces variabilis has demonstrated ...