Browsing Annual Medical Student Research Forum by Issue Date
Now showing items 1-20 of 276
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Impact of Donor Age on Endothelium-Descemet Membrane Layer Harvesting and Roll Formation
(2013-01-22)PURPOSE: Descemet membrane endothelial keratoplasty (DMEK) is an alternative to Descemet's stripping automated endothelial keratoplasty (DSAEK) to surgically replace diseased corneal endothelium. Although graft rejection ... -
Attitudes and Trends in the Treatment of Morphea: A National Study
(2013-01-22)INTRODUCTION: Morphea, or localized scleroderma, is an inflammatory disorder of both adults and children that can lead to severe cosmetic and functional impairment due to excess collagen deposition in the dermis and ... -
Automated Analysis of Electroglottographic Signal in Adductor Spasmodic Dysphonia
(2013-01-22)INTRODUCTION: The human voice can be evaluated by a variety of methods. Electroglottographic (EGG) signal is produced when vocal fold vibrations produce cyclic fluctuation in the electrical impedance across the larynx. The ... -
Obesity and Outcomes Following Burns in the Pediatric Population
(2013-01-22)PURPOSE: While obesity is associated with increased mortality and decreased functional outcomes in adult burn patients, the ramifications of larger than average body size in the pediatric burn population are less well ... -
Parameters that Predict for High Grade Rectal Toxicity in Prostate Cancer Patients Undergoing Stereotactic Body Radiation Therapy- Analysis of Phase I/II at UT Southwestern
(2013-01-22)INTRODUCTION: Conventional radiation therapy (CRT) is a well-accepted option for PCa treatment with high disease control rate, and low (< 3-5%) risk of rectal toxicity. SBRT, unlike CRT, delivers higher doses of radiation ... -
Folate Receptor Beta Targeting for In Vivo Optical Imaging of Head and Neck Squamous Cell Carcinoma
(2013-01-22)OBJECTIVE: The folate receptor (FR) is a high-affinity folic acid binding endocytic receptor uncommonly expressed in normal tissues. The α isoform (FR-α) is overexpressed in a variety of epithelial neoplastic cells. In ... -
The University of Texas Southwestern Medical Center at Dallas Fifty-First Annual Student Research Forum
(2013-01-22)This 100-page booklet includes a list of oral presentations, a table of contents to the abstracts, and the abstracts divided by three categories: Basic Research and Disease Models, Research Design and Methods, Clinical ... -
NF-kB Mediates Cartilage Degradation induced by Trauma Injury and IL-1
(2013-01-22)BACKGROUND: IL-1 is one of the major pro-inflammatory cytokines responsible for cartilage degradation. Several studies have shown that IL-1 mediates the upregulation of tissue degradation through the NF-κB and Mitogen-activated ... -
An Automated Tool for Measuring Aortic Pulse Wave Velocity
(2013-01-22)PURPOSE: Aortic Pulse wave Velocity (APV) has been shown to be associated with end organ damage independent of age, sex, and hypertension duration. The purpose of this study is to evaluate an automated approach for computing ... -
Evaluation of Transcutaneous Bilirubinometry (TcB) in the First Hours of Life to Predict Subsequent Invasive Bilirubin Testing during the Birth Hospitalization
(2013-01-22)BACKGROUND: TcB is well-established for non-invasive bedside monitoring of trends in neonatal bilirubin values. It is not known whether an ETcB value will assist in (a) predicting subsequent TcB values, or (b) the need for ... -
The Diagnostic Dilemma of Identifying Perforated Appendicitis
(2013-01-22)BACKGROUND: Despite 61 clinical trials on pediatric appendicitis in the Cochrane database over the last decade, a defined best clinical pathway for acute versus complicated appendicitis remains lacking. The lack of accuracy ... -
A Quantitative Study of Parathyroid (1-34) and Bone Morphogenetic Protein-2 on Spinal Fusion Outcomes in a Rabbit Model of Lumbar Dorsolateral Intertransverse Process Arthrodesis
(2013-01-22)INTRODUCTION: Lumbar spinal fusion is a common neurosurgical procedure. Over 250,000 lumbar spinal fusion operations are performed annually in the U.S. and, by far, dorsolateral intertransverse process arthrodesis (DIPA) ... -
Argon Laser Trabeculoplasty (ALT): Predictors of Failure
(2013-01-22)PURPOSE. ALT is widely used to control intraocular pressure (IOP) in glaucoma. We wished to determine predictive factors for long term success of ALT performed by supervised residents in training on patients at a local VA ... -
Confirmation of Hypoglycemia in Goat -/- Mice When Total Body Fat Falls below 2% of Body Weight
(2013-01-22)Ghrelin is an octanoylated peptide hormone first identified in stomach, with the octanoyl group being essential to its biological activity. The enzyme that attaches the octanoyl group to ghrelin is called Ghrelin-Oacyltransferase ... -
The Radiation Footprint on the Pediatric Trauma Patient
(2013-01-22)BACKGROUND: Overuse of radiation in patients has recently become an important topic of discussion within the medical community. Pediatric patients are most at risk. A recent study has proven the incidence of 1 brain tumor ... -
Speech and Language Performance of 3 Year Old Children Born Preterm: A Preliminary Report
(2013-01-22)INTRODUCTION: The association between preterm birth and an increased risk for cognitive impairment and academic struggles later in life is well established. In particular, the tendency for preterm infants to show delayed ... -
Selective Laser Trabeculoplasty (SLT): Predictors of Failure
(2013-01-22)PURPOSE. SLT is widely used to control intraocular pressure (IOP) in glaucoma. We wished to determine predictive factors for long term success of SLT performed by full time faculty at a University Eye Clinic in Dallas. METHODS. ... -
AB1-42 Antibody Producing Plasma Cells in DNA AB42 Trimer Immunized Mice Reside Predominantly in the Bone Marrow
(2013-01-22)Alzheimer's disease (AD) is the most common form of age-related dementia and affects nearly 40 million people worldwide. Immunotherapy provides a possible avenue for prophylaxis of AD, but a clinical trial (AN1792) in which ... -
Analysis of Free Flap Breast Reconstruction Failures: Are Specific Patient Characteristics Associated with Free Flap Failure?
(2013-01-22)PURPOSE: This study was performed to gain insight on the patients who have undergone free flap breast reconstructive surgery. Recognizing certain patient variables, as risk factors for developing free flap failure, is ... -
Regulation of Pyruvate Kinase M2 (PKM2) Expression and Activity in Cardiac Hypertrophy
(2013-01-22)BACKGROUND: Cardiac hypertrophy is characterized by robust structural, metabolic, and signaling events, which include increased myocyte size and width, increased glycolytic flux, aerobic glycolysis, and induction of ...