Browsing Annual Medical Student Research Forum by Issue Date
Now showing items 1-20 of 299
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AB1-42 Antibody Producing Plasma Cells in DNA AB42 Trimer Immunized Mice Reside Predominantly in the Bone Marrow
(2013-01-22)Alzheimer's disease (AD) is the most common form of age-related dementia and affects nearly 40 million people worldwide. Immunotherapy provides a possible avenue for prophylaxis of AD, but a clinical trial (AN1792) in which ... -
Attitudes and Trends in the Treatment of Morphea: A National Study
(2013-01-22)INTRODUCTION: Morphea, or localized scleroderma, is an inflammatory disorder of both adults and children that can lead to severe cosmetic and functional impairment due to excess collagen deposition in the dermis and ... -
Confirmation of Hypoglycemia in Goat -/- Mice When Total Body Fat Falls below 2% of Body Weight
(2013-01-22)Ghrelin is an octanoylated peptide hormone first identified in stomach, with the octanoyl group being essential to its biological activity. The enzyme that attaches the octanoyl group to ghrelin is called Ghrelin-Oacyltransferase ... -
Selective Laser Trabeculoplasty (SLT): Predictors of Failure
(2013-01-22)PURPOSE. SLT is widely used to control intraocular pressure (IOP) in glaucoma. We wished to determine predictive factors for long term success of SLT performed by full time faculty at a University Eye Clinic in Dallas. METHODS. ... -
Acute Effect of High vs Low Dialysate Sodium on Endothelial Cell Function During Hemodialysis
(2013-01-22)BACKGROUND: Intradialytic hypertension (HTN), a rise in blood pressure that occurs during hemodialysis (HD) treatments in up to 15% of patients, is associated with higher morbidity and mortality. The cause of intradialytic ... -
Evolving Characteristics of HIV Infected Pregnancies at a Single Institution
(2013-01-22)OBJECTIVE: Over the past 26 years, significant advances have been made in the understanding and management of patients infected with HIV. We sought to determine if these changes in HIV care have had an impact on the ... -
The Wait for the Weight: Pediatricians' Communication about Weight to Overweight and Obese Latino Children and their Parents
(2013-01-22)BACKGROUND: Latinos are among the most overweight (OW) racial/ethnic groups of US children. It is unknown, however, whether language barriers impact the communication of childhood OW. Objective: To determine whether and ... -
Searching for Genes of Host Defense
(2013-01-22)Through random mutation of the mouse genome and phenotypic screening of the mutated mice, genes can be identified that are associated with dysfunction in the innate immune system. The strategy proposed works under the ... -
Intravascular Ultrasonography Analysis of the Everolimus-Eluting Stent in Coronary Chronic Total Occlusions
(2013-01-22)PURPOSE: Coronary artery disease (CAD) is consistently the number one cause of death for both men and women worldwide. Of the millions of patients diagnosed with CAD, approximately 1 in 5 is found to have a coronary artery ... -
The Diagnostic Dilemma of Identifying Perforated Appendicitis
(2013-01-22)BACKGROUND: Despite 61 clinical trials on pediatric appendicitis in the Cochrane database over the last decade, a defined best clinical pathway for acute versus complicated appendicitis remains lacking. The lack of accuracy ... -
Barbed Sutures and Wound Complications in Plastic Surgery
(2013-01-22)GOALS: Technological advancements, along with their refinements, have substantially increased the amount of wound closure tools at the disposal of the surgeon. Barbed sutures, with a unique design containing circumferentially ... -
Impact of Donor Age on Endothelium-Descemet Membrane Layer Harvesting and Roll Formation
(2013-01-22)PURPOSE: Descemet membrane endothelial keratoplasty (DMEK) is an alternative to Descemet's stripping automated endothelial keratoplasty (DSAEK) to surgically replace diseased corneal endothelium. Although graft rejection ... -
Parameters that Predict for High Grade Rectal Toxicity in Prostate Cancer Patients Undergoing Stereotactic Body Radiation Therapy- Analysis of Phase I/II at UT Southwestern
(2013-01-22)INTRODUCTION: Conventional radiation therapy (CRT) is a well-accepted option for PCa treatment with high disease control rate, and low (< 3-5%) risk of rectal toxicity. SBRT, unlike CRT, delivers higher doses of radiation ... -
Cdk5-Dependent Regulation of Neuronal MEK1
(2013-01-22)INTRODUCTION: Cyclin-dependent protein kinase 5 (Cdk5) is a member of the Cdk family that is implicated in many regulatory pathways in post-mitotic neurons. The kinase plays an important role in neuronal development and ... -
Discordance in OR Safety Attitudes: Does Safety Lie in the Eye of the Beholder?
(2013-01-22)BACKGROUND: Efforts to improve operating room (OR) safety can be optimized if we understand the safety attitudes of those who work in the OR. We sought to describe the safety attitudes of current OR personnel. METHODS: ... -
Anticoagulant Use is Associated with Improved Biochemical Control of High-Risk Prostate Cancer Patients Treated with Radiation Therapy
(2013-01-22)INTRODUCTION: The coagulation system modulates multiple cancer pathways, including tumor proliferation, angiogenesis, host immunologic defense, and metastasis. Prior studies have reported improved survival and freedom from ... -
Analysis of Free Flap Breast Reconstruction Failures: Are Specific Patient Characteristics Associated with Free Flap Failure?
(2013-01-22)PURPOSE: This study was performed to gain insight on the patients who have undergone free flap breast reconstructive surgery. Recognizing certain patient variables, as risk factors for developing free flap failure, is ... -
Automated Analysis of Electroglottographic Signal in Adductor Spasmodic Dysphonia
(2013-01-22)INTRODUCTION: The human voice can be evaluated by a variety of methods. Electroglottographic (EGG) signal is produced when vocal fold vibrations produce cyclic fluctuation in the electrical impedance across the larynx. The ... -
Regulation of Pyruvate Kinase M2 (PKM2) Expression and Activity in Cardiac Hypertrophy
(2013-01-22)BACKGROUND: Cardiac hypertrophy is characterized by robust structural, metabolic, and signaling events, which include increased myocyte size and width, increased glycolytic flux, aerobic glycolysis, and induction of ... -
NF-kB Mediates Cartilage Degradation induced by Trauma Injury and IL-1
(2013-01-22)BACKGROUND: IL-1 is one of the major pro-inflammatory cytokines responsible for cartilage degradation. Several studies have shown that IL-1 mediates the upregulation of tissue degradation through the NF-κB and Mitogen-activated ...