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Analyses of the Link Between Amyloid and Tau Pathology in an AD Mouse Model (3xtg-AD): Disease Progression with Increased Levels of Abeta and Tau Peptides
INTRODUCTION: Pathological features of Alzheimer's disease (AD) include the accumulation of extracellular amyloid plaques composed of aggregated amyloid-β (Aβ) peptide and intracellular neurofibrillary tangles consisting ...
Potential Impact of the Site-Neutral Payment Policy on Regions and Hospitals with Differential LTAC Utilization: A National Study of Medicare Beneficiaries
BACKGROUND: Long-term acute care hospitals (LTAC) are the fastest growing and most expensive post-acute care provider. Due to rising LTAC use, beginning in 2018 the site-neutral payment (SNP) policy will reduce reimbursement ...
Increased Rates of Readmission, Reoperation, and Mortality Following Open Reduction and Internal Fixation of Ankle Fractures Are Associated with Diabetes Mellitus
BACKGROUND: Ankle fractures are amongst the most common type of fracture injury in adults with an annual incidence of 187 fractures per 100,000 people in the United States. Previous groups have shown that diabetes mellitus ...
Safety of Tumor Necrosis Factor Inhibitor Use in Patients with Concomitant Malignancy
BACKGROUND: Tumor necrosis factor (TNF) inhibitors are considered contraindicated in patients with a history of malignancy. However, data to support this notion is limited. We hypothesize TNF inhibitors can be used safely ...