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From Flies to Mice: Drosophila as a Model System to Study Fat Biology
Adipose tissues are found in a wide range of animal species ranging from invertebrates to mammals and are essential for many aspects of the animal life cycle. Fat biology has taken on a new and urgent importance as it is ...
Regulation of Transcription by Poly(Adp-Ribose) Polymerase-1 in Adipogenesis and Inflammation
Poly(ADP-ribose) polymerases (PARPs) comprise a family of enzymes sharing a conserved catalytic domain that supports mono- or poly(ADP-ribosyl)transferase activity. PARP-1 is the founding member and controls transcriptional ...