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The Role of Serine Protease Inhibitors in Regulating Hepatotoxicity During Viral Infection
Major hepatitis viruses, such as HBV and HCV, are not directly cytopathic; instead liver injury is due to a vigorous immune response. Cytotoxic T lymphocytes (CTL) and natural killer (NK) cells kill virally infected and ...
The Roles of Major Histocompatibility Complex Class I and Foxk1 in Natural Killer Cell Development
Pathways leading to the development of functionally mature Natural Killer cells from bone marrow progenitors are incompletely characterized. Several reports have indicated the necessity of class I Major Histocompatibility ...
Role of Nlc Cells in Murine Models of T Cell-Dependent Responses
NK cells are part of the innate immune system, yet they can also modulate the acquired immune response. Activated NK cells, for instance, can increase antigen specific IgG2a production in response to T independent responses, ...