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A WNK and a Nudge Towards Kinase Biology
A family of four atypical protein kinases; WNKs are characterized by a non-canonical position of the catalytic lysine. The significance of WNKs was first realized when they were found to be causatively linked to a rare ...
The Hippo Signaling Pathway in Organ Size Control and Regeneraton
The Hippo (Hpo) signaling pathway controls cell growth, proliferation and apoptosis in both Drosophila and vertebrates. Our lab has previously demonstrated that Hpo signaling regulates gene expression by inhibiting a ...