UT Southwestern Medical School
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Welcome to the UT Southwestern Medical School’s electronic theses and dissertations (ETD) collection.
Most UT Southwestern ETDs are subject to a default embargo period of two (2) years from the date of degree conferral. These embargoed ETDs are unavailable until the embargo expires.
It might be possible to contact the author for more information before the end of the embargo. For assistance or more information, please contact the UT Southwestern Medical School Dean’s Office by email.
To verify whether an ETD is available or if you have other questions, please contact etd-utsw@utsouthwestern.edu.
Recent Submissions
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Epidemiology of Burns Treated by Yekatit 12 Burn Unit in 2016
(2017-04-03)BACKGROUND: Burns contribute significantly to the burden of disease, particularly in low and middle-income countries. There is a paucity of data regarding the epidemiology of burns in Ethiopia, and about burn injuries in ... -
Benchmarking Surgical Quality: Cholecystectomy at a Safety-Net Hospital
(2017-04-03)BACKGROUND: Rates of conversion from laparoscopic to open cholecystectomy in the U.S. have been reported to be 5 to 10%. This study aims to benchmark conversion rate and identify preoperative factors that are predictive ... -
Transcriptional and Cytokine Profiles Identify CXCL9 as a Biomarker of Disease Activity in Morphea
(2017-03-31)Interferon-related pathways have not been studied in morphea and biomarkers are needed. We sought to characterize morphea serum cytokine imbalance and interferon-related gene expression in blood and skin to address this ... -
Assessment of Dermatology Clinic Resources at Safety-Net Hospitals: Results from a National Survey
(2017-03-24)BACKGROUND: The extent of resources available to outpatient dermatology clinics at safety-net hospitals providing care to the underserved is not well characterized. Identification of resource gaps can direct strategies ... -
Epidemiology of Traumatic Brain Injuries at a Major Government Hospital in Cambodia
(2017-03-02)BACKGROUND: Traumatic brain injury (TBI) is a critical public health problem worldwide with a significant socioeconomic burden. While improved safety regulations in high-income countries have resulted in a decline in ... -
Effects of Size on Ovoid Anterior Septal Perforations: Physiologic Modeling With Computational Fluid Dynamics
(2016-04-04)BACKGROUND: Nasal septal perforations (NSPs) often cause bleeding, crusting, obstruction, and/or whistling. Exposed cartilage along the perimeter of the perforation prolongs healing time. The perforation perimeter lies in ... -
The Burden of Gunshot Injuries on Orthopaedic Healthcare Resources in South Africa
(2016-04-07)BACKGROUND: Injuries inflicted by gunshot wounds (GSW) are an immense burden on the South African healthcare system. In 2005, Allard et al. estimated South African state hospitals treat approximately 127,000 firearm victims ... -
Gamification of Exercise and Its Application for Fall Prevention Among Patients with Diabetes and Peripheral Neuropathy
(2016-04-04)BACKGROUND: Individuals with diabetic peripheral neuropathy (DPN) often experience concomitant impaired proprioception and postural instability. Diminished peripheral sensory input, as found in DPN, has been associated ... -
Modulating SIRP-alpha, a Myeloid-Specific Immune Checkpoint, for Immunotherapeutic Treatment of Malignancy
(2016-04-01)BACKGROUND: CD47 is a "don't-eat-me" signal upregulated by many types of cancer that signals through its receptor SIRPα to inhibit macrophage-mediated destruction. Recent studies have demonstrated the efficacy of anti-CD47 ... -
Accuracy in Diagnosing Pediatric Appendicitis: Discordance in Diagnosis and Masqueraders
(2016-04-04)BACKGROUND: The classification of perforated versus nonperforated appendicitis remains poorly defined despite being clinically significant and requiring dramatically different therapeutic approaches. We hypothesized that ... -
Isoflurane Preserves Viability of Highly Metabolic Renal Epithelial Cells Exposed to Anoxia
(2016-04-01)BACKGROUND: Cells subjected to ischemia, whether in the context of hypoxia, hypovolemia, or circulatory collapse, undergo damage and death as a result of oxygen deprivation. Previous studies have shown that general anesthetics ... -
Leptospirosis Risk Perception and Associated Behavior in a Region of High Seroprevalence in Iquitos, Peru
(2016-04-01)BACKGROUND: Iquitos has an ideal environment for Leptospira transmission leading up to endemic leptospirosis. Studies in Belen, an urban slum in Iquitos, indicate seroprevalence as high as 28% with rates higher in flooding ... -
Long-Term Management of Luminal Urethral Stricture in Women
(2016-04-01)BACKGROUND: Luminal urethral strictures (LUS), though rare, are very bothersome conditions that can cause significant voiding symptoms and adversely affect women's' quality of life. Urethral dilation (UD) is commonly ... -
Identification of ITGBL1: A Novel Regulator of Adipogenesis
(2016-04-01)BACKGROUND: Obesity is a global epidemic that increases the risk of chronic metabolic disease. The rising burden of human suffering inflicted by the double-edged sword of obesity and diabetes has increased the urgency of ... -
Quantitative Assessment of Synovitis in Legg-Calve-Perthes Disease Using Gadolinium Enhanced MRI
(2016-04-01)PURPOSE: Hip synovitis in LCPD is associated with pain, decreased motion, and poor outcome. However, a reliable quantitative method to assess hip synovitis, its progression, and response to therapy is not currently available. ... -
A Simplified Risk Score for Predicting the Incidence of Major Complications after Complex Abdominal-Pelvic Resections
(2016-04-01)BACKGROUND: The POSSUM system is used to predict risk of complications following general surgical procedures. This 18-factor instrument has been challenging to apply to most surgical oncology patient populations. Our aim ... -
Proteomic Discovery of Functionally Important Pathways in Myocardial Ischemia-Reperfusion Injury
(2016-04-01)BACKGROUND: Coronary heart disease, a source of myocardial ischemia-reperfusion injury (IRI), is the world's leading cause of death and disability. Insulin-like growth factor 1 (IGF1) transgenic (Tg) mouse hearts are ... -
Beating the Weekend Trend: Increased Mortality in Older Adult Traumatic Brain Injury (TBI) Patients Admitted on Weekends
(2015-04-03)BACKGROUND: Weekend admission is associated with mortality in cardiovascular emergencies and stroke but the effect of weekend admission for trauma is not well defined. We sought to determine whether differences in mortality ... -
Patient Characteristics Associated With Adherence to Phototherapy
(2015-03-31)BACKGROUND: The therapeutic efficacy of phototherapy is dependent on regular visits over extended time periods. There is concern among dermatologists regarding the feasibility of phototherapy in the face of increasing ... -
A DRM Study of Trauma Memory Among Employees of New York City Companies Affected by the September 11, 2001 Attacks
(2015-03-24)BACKGROUND: PTSD has been found to be associated with abnormalities in memory function. This relationship has not previously been studied with the Deese-Roediger-McDermott (DRM) false memory paradigm in disaster-exposed ...
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