Medication Adherence in Children and Adolescents with Major Depressive Disorder

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dc.contributor.advisorHughes, Carroll W.en
dc.creatorSternweis, Kathryn VanArsdaleen
dc.date.accessioned2010-07-12T17:44:53Z
dc.date.available2010-07-12T17:44:53Z
dc.date.issued2006-08-11
dc.description.abstractMajor Depressive Disorder (MDD) is a serious psychiatric disorder in children and adolescents where antidepressant adherence remains an important issue. The present study uses electronic monitoring (Medication Event Monitoring System, APREX, Fremont, California [MEMSĀ® caps]) to compare various methods of measuring adherence. Subjects who met the Diagnostic and Statistical Manual of Mental Disorders' (DSM-IV) criteria for MDD participated in a randomized controlled trial involving fluoxetine. A subset of patients had their medication adherence monitored for up to 12 weeks using MEMS caps, blood levels, self-report, medication diaries, physicians' estimates, and pill counts. Throughout the 12-week process, patients also completed a number of questionnaires assessing treatment expectancy, side effects, family functioning, school functioning, cognitive beliefs, depressive symptoms, and the identity of the individual(s) dispensing medication.en
dc.format.digitalOriginborn digitalen
dc.format.mediumElectronicen
dc.format.mimetypeapplication/pdfen
dc.identifier.oclc182523596
dc.identifier.urihttps://hdl.handle.net/2152.5/359
dc.language.isoenen
dc.subjectMedication Adherenceen
dc.subjectChildrenen
dc.subjectDepressive Disorder, Majoren
dc.titleMedication Adherence in Children and Adolescents with Major Depressive Disorderen
dc.typeThesisen
dc.type.genredissertationen
dc.type.materialTexten
thesis.date.available2006-08-11
thesis.degree.departmentGraduate School of Biomedical Sciencesen
thesis.degree.disciplineClinical Psychologyen
thesis.degree.grantorUT Southwestern Medical Centeren
thesis.degree.levelDoctoralen
thesis.degree.nameDoctor of Philosophyen

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