Paclitaxel-Eluting Vs. Bare Metal Stent Implantation in Saphenous Vein Graft Lesions: Very Long-Term Follow-up of the SOS (Stenting of Saphenous Vein Grafts) Trial

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dc.contributor.otherChao, Howarden
dc.contributor.otherGuerra, Andresen
dc.contributor.otherHan, Henryen
dc.contributor.otherChristopoulos, Georgeen
dc.contributor.otherde Lemos, James A.en
dc.contributor.otherObel, Owenen
dc.contributor.otherAddo, Tayoen
dc.contributor.otherRoesle, Micheleen
dc.contributor.otherHaagen, Donalden
dc.contributor.otherRangan, Bavana V.en
dc.contributor.otherBanerjee, Subhashen
dc.contributor.otherBrilakis, Emmanouil S.en
dc.creatorSosa, Alanen
dc.date.accessioned2015-02-18T16:17:22Z
dc.date.available2015-02-18T16:17:22Z
dc.date.issued2015-01-26
dc.descriptionThe 53rd Annual Medical Student Research Forum at UT Southwestern Medical Center (Monday, January 26, 2015, 2-5 p.m., D1.602)en
dc.description.abstractBACKGROUND: The very long-term (>3 year) outcomes after implantation of drug-eluting as compared with bare metal stents (BMS) in saphenous vein grafts (SVGs) have received limited study. METHODS: In the Stenting Of Saphenous vein grafts (SOS) trial 80 patients were randomized to BMS or paclitaxel-eluting stents (PES). During a median follow-up of 35 months use of PES was associated with better clinical outcomes. We report very long-term outcomes on 62 patients enrolled at the highest enrolling institution. RESULTS: Of the 62 studied patients 31 received a BMS and 31 a PES. Both study groups had similar baseline characteristics. During a median follow-up of 6.9 years the study patients experienced 116 major adverse cardiovascular events (MACE). Compared with patients who received BMS those who received PES had lower incidence of MACE (hazard ratio [HR]=0.56, P=0.04), target lesion revascularization (HR=0.20, P=0.001), target vessel revascularization (HR 0.41, P=0.02), target vessel failure (HR=0.35, P=0.001), and definite or probable stent thrombosis (HR=0.14, P=0.03). There was no significant difference in all-cause mortality (HR=1.77, P=0.15) and myocardial infarction (HR=0.52, P=0.10) between the two groups. CONCLUSION: The early benefit observed with use of PES vs BMS in SVGs persisted during very long-term follow-up.en
dc.description.sponsorshipSouthwestern Medical Foundationen
dc.identifier.citationSosa, A., Chao, H., Guerra, A., Han, H., Christopoulos, G., de Lemos, J. A., . . . Brilakis, E. S. (2015, January 26). Paclitaxel-eluting vs. bare metal stent impantation in saphenous vein graft lesions: very long-term follow-up of the SOS (stenting of saphenous vein grafts) trail. Poster presented at the 53rd Annual Medical Student Research Forum, Dallas, TX. Retrieved from https://hdl.handle.net/2152.5/1544en
dc.identifier.urihttps://hdl.handle.net/2152.5/1544
dc.language.isoenen
dc.relation.ispartofseries53rd Annual Medical Student Research Forumen
dc.subjectClinical Research and Case Reportsen
dc.subject.meshAngioplasty, Balloon, Coronaryen
dc.subject.meshCardiovascular Agentsen
dc.subject.meshCoronary Artery Bypassen
dc.subject.meshDrug-Eluting Stentsen
dc.subject.meshGraft Occlusion, Vascularen
dc.subject.meshMetalsen
dc.subject.meshPaclitaxelen
dc.subject.meshSaphenous Veinen
dc.subject.meshStentsen
dc.titlePaclitaxel-Eluting Vs. Bare Metal Stent Implantation in Saphenous Vein Graft Lesions: Very Long-Term Follow-up of the SOS (Stenting of Saphenous Vein Grafts) Trialen
dc.typePresentationen

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